Nickel-catalyzed triarylamine synthesis: synthetic and mechanistic aspects.
نویسندگان
چکیده
An improved protocol was described for the amination of chloroarenes with diarylamines under NiCl2(PCy3)2 catalysis in the presence of a Grignard reagent as base. This method fully suits bromo-/iodoarene substrates as well, and even is expanded to certain aryl tosylates. A preliminary investigation into the mechanism suggests that this amination reaction might proceed through Ni(I) and Ni(III) intermediates rather than via the usually expected Ni(0)-Ni(II) cycle.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 8 شماره
صفحات -
تاریخ انتشار 2014